NASCOBAL® (Cyanocobalamin, USP) Nasal Spray is a prescription medicine used as a supplement to treat vitamin B12 deficiency. NASCOBAL® is the only FDA-approved vitamin B12 nasal spray. It is clinically proven to have increased and maintained healthy serum vitamin B12 levels. NASCOBAL® is a tasteless and odorless fine mist with a convenient, once-weekly dosing regimen: 1 spray, 1 nostril, 1x a week.

The only FDA-approved prescription vitamin B12 nasal spray

Here are some features of this product:

  • Once-weekly nasal spray
    Fewer visits to the doctor’s office for vitamin B12 dose
    Not a painful shot
  • Tasteless and odorless fine mist
  • Helps to increase and maintain vitamin B12 levels
  • Absorbed directly into the bloodstream—designed to bypass the digestive tract
  • Self-administered

Do not drink hot liquids or eat hot foods 1 hour before
and 1 hour after taking NASCOBAL® Nasal Spray.

  • Achieved mean peak serum vitamin B12 concentration within 1.5 hours
  • Reached mean peak concentration of 1021 pg/mL
  • At 72 hours, mean serum vitamin B12 level was increased by 46% above baseline

†In 21 healthy volunteers under fasting conditions, a single
*500-mcg dose of NASCOBAL® was given and monitored for 3
*days. Data are based on baseline uncorrected serum vitamin *B12 levels.


*Patients may redeem this offer ONLY when accompanied by a valid prescription for NASCOBAL® Nasal Spray. Offer is valid for costs exceeding $25 to a maximum benefit of $100. Offer is not valid for patients whose prescriptions are reimbursed in whole or in part under Medicaid, Medicare, Medigap, VA, DoD, TRICARE, or any other federal or state programs (such as medical assistance programs) or where prohibited by law. Offer is not valid in VT or where prohibited in whole or in part. This offer may be amended or ended at any time without notice.