NASCOBAL®
nasal spray

The first FDA-approved prescription vitamin B12 nasal spray1

A well-established way to deliver vitamin B12

  • Intranasal delivery
  • Designed to bypass the gastrointestinal (GI) tract and deliver vitamin B12 directly into the bloodstream through the nasal mucosa2
  • Not a painful injection
  • Clinically proven to have increased and maintained vitamin B12 levels3
  • Convenient, once-weekly dosing regimen4
  • Self-administered, tasteless and odorless fine mist
  • 1 spray, 1 nostril, 1x a week4
  • Eligible patients may pay as little as $0 per month*

Patients may redeem this offer ONLY when accompanied by a valid prescription. Offer is valid up to a maximum benefit of $150. Offer is not valid for patients whose prescriptions are reimbursed in whole or in part under Medicaid, Medicare, Medigap, VA, DoD, TRICARE, or any other federal or state programs (such as medical assistance programs) or where otherwise prohibited by law. Offer is not valid in VT or where prohibited in whole or in part. This offer may be amended or ended at any time without notice.

Clinically proven to have increased vitamin B12 levels from the first dose3

vitaminb12-mean-concentration
  • Achieved mean peak serum vitamin B12 concentration within 1.5 hours3†
  • Reached mean peak concentration of 1021 pg/mL3†
  • At 72 hours, mean serum vitamin B12 level was increased by 46% above baseline3†

In 21 healthy volunteers under fasting conditions, a single 500 mcg dose of NASCOBAL® was given and monitored for 3 days. Data are based on baseline uncorrected serum vitamin B12 levels.

How to use NASCOBAL® Nasal Spray

nasal-spray-step1-hcp
  • The unit contains only 1 spray:
    DO NOT prime before use
  • Blow nose gently to clear both nostrils
  • Hold the unit with your thumb, supporting it at the bottom, and your index and middle fingers on either side of the nozzle
nasal-spray-step2-hcp
  • Gently close 1 nostril with your other index finger. Insert the nozzle into open nostril approximately ½ inch, or as far as feels comfortable, and tilt your head slightly forward. Do not press the plunger yet
  • Breathe in gently through your nose, close your mouth, and at the same time, press the plunger firmly with your thumb
nasal-spray-step3-hcp
  • Remove the nozzle from your nostril. At the same time, keep your head level for 10 to 20 seconds while gently breathing in through your nose and breathing out through your mouth
NASCOBAL® Nasal Spray should be administered at least one hour before or one hour after ingestion of hot foods or liquids.

Dose adjustments may be required.